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| Molecular Profile | FGFR1 V561M |
| Therapy | 3D185 |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR1 V561M | Advanced Solid Tumor | predicted - sensitive | 3D185 | Preclinical - Biochemical | Actionable | In a preclinical study, 3D185 inhibited kinase activity of FGFR1 V561M in an in vitro assay (PMID: 31438996). | 31438996 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (31438996) | Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models. | Full reference... |