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Molecular Profile BRAF T599dup
Therapy Cetuximab
Indication/Tumor Type colorectal cancer
Response Type resistant

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF T599dup colorectal cancer resistant Cetuximab Preclinical - Pdx Actionable In preclinical study, a colorectal cancer patient-derived xenograft (PDX) model harboring BRAF T599dup was resistant to Erbitux (cetuximab) treatment (PMID: 31515458). 31515458
PubMed Id Reference Title Details
(31515458) Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer. Full reference...