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Molecular Profile | BRAF K601E |
Therapy | Panitumumab |
Indication/Tumor Type | colorectal cancer |
Response Type | predicted - resistant |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF K601E | colorectal cancer | predicted - resistant | Panitumumab | Case Reports/Case Series | Actionable | In a clinical study, Vectibix (panitumumab) treatment as a third-line therapy resulted in progressive disease in a metastatic colorectal cancer patient harboring BRAF K601E (PMID: 31515458). | 31515458 |
PubMed Id | Reference Title | Details |
---|---|---|
(31515458) | Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer. | Full reference... |