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Molecular Profile | PIK3CA mutant |
Therapy | BAY1082439 |
Indication/Tumor Type | stomach cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
PIK3CA mutant | stomach cancer | sensitive | BAY1082439 | Preclinical | Actionable | In a preclinical study, BAY1082439 inhibited growth of gastric cancer cells harboring PIK3CA mutations in culture and xenograft models (AACR; 2015. Abstract nr 2674). | detail... |
PubMed Id | Reference Title | Details |
---|---|---|
Activity of BAY1082439, a balanced PI3Kalpha/beta inhibitor, in gastric cancer | Full reference... |