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| Molecular Profile | PIK3CA E545K |
| Therapy | LY294002 |
| Indication/Tumor Type | esophagus squamous cell carcinoma |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| PIK3CA E545K | esophagus squamous cell carcinoma | sensitive | LY294002 | Preclinical | Actionable | In a preclinical study, LY294002 inhibited cell proliferation of esophagus squamous cell carcinoma cells expressing PIK3CA E545K (PMID: 18262558). | 18262558 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (18262558) | PIK3CA mutation status in Japanese esophageal squamous cell carcinoma. | Full reference... |