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Molecular Profile | PIK3CA E545K |
Therapy | LY294002 |
Indication/Tumor Type | esophagus squamous cell carcinoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
PIK3CA E545K | esophagus squamous cell carcinoma | sensitive | LY294002 | Preclinical | Actionable | In a preclinical study, LY294002 inhibited cell proliferation of esophagus squamous cell carcinoma cells expressing PIK3CA E545K (PMID: 18262558). | 18262558 |
PubMed Id | Reference Title | Details |
---|---|---|
(18262558) | PIK3CA mutation status in Japanese esophageal squamous cell carcinoma. | Full reference... |