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Molecular Profile | BRAF V600E |
Therapy | Vemurafenib |
Indication/Tumor Type | ovarian serous cystadenocarcinoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E | ovarian serous cystadenocarcinoma | predicted - sensitive | Vemurafenib | Case Reports/Case Series | Actionable | In a clinical case study, Zelboraf (vemurafenib) treatment resulted in a complete radiological response that lasted for 3 years in a patient with low-grade serous cystadenocarcinoma of the ovary harboring BRAF V600E (PMID: 36967525). | 36967525 |
PubMed Id | Reference Title | Details |
---|---|---|
(36967525) | Deep and lasting response and acquired resistance to BRAFV600E targeting in a low-grade ovarian cancer patient. | Full reference... |