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Molecular Profile | IDH2 R172K |
Therapy | SH1573 |
Indication/Tumor Type | hematologic cancer |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
IDH2 R172K | hematologic cancer | predicted - sensitive | SH1573 | Preclinical - Biochemical | Actionable | In a preclinical study, SH1573 inhibited the activity of IDH2 R172K in an in vitro assay (PMID: 34221866). | 34221866 |
PubMed Id | Reference Title | Details |
---|---|---|
(34221866) | Preclinical efficacy against acute myeloid leukaemia of SH1573, a novel mutant IDH2 inhibitor approved for clinical trials in China. | Full reference... |