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| Molecular Profile | ATM Q1331H ATM I1441fs |
| Therapy | Radiotherapy |
| Indication/Tumor Type | lung non-small cell carcinoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| ATM Q1331H ATM I1441fs | lung non-small cell carcinoma | predicted - sensitive | Radiotherapy | Case Reports/Case Series | Actionable | In a retrospective analysis, radiotherapy treatment resulted in 3.1 months of local disease control and no in-field recurrence in a patient with non-small cell lung cancer harboring ATM I1441fs and Q1331H (PMID: 28055970). | 28055970 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (28055970) | Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM. | Full reference... |