Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Molecular Profile | ATM Q1331H ATM I1441fs |
Therapy | Radiotherapy |
Indication/Tumor Type | lung non-small cell carcinoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
ATM Q1331H ATM I1441fs | lung non-small cell carcinoma | predicted - sensitive | Radiotherapy | Case Reports/Case Series | Actionable | In a retrospective analysis, radiotherapy treatment resulted in 3.1 months of local disease control and no in-field recurrence in a patient with non-small cell lung cancer harboring ATM I1441fs and Q1331H (PMID: 28055970). | 28055970 |
PubMed Id | Reference Title | Details |
---|---|---|
(28055970) | Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM. | Full reference... |