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| Molecular Profile | ATM R1875* |
| Therapy | Radiotherapy |
| Indication/Tumor Type | colon cancer |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| ATM R1875* | colon cancer | predicted - sensitive | Radiotherapy | Case Reports/Case Series | Actionable | In a retrospective analysis, radiotherapy treatment resulted in 3.8 months of local disease control and no in-field recurrence in a patient with colon cancer harboring ATM R1875* (PMID: 28055970). | 28055970 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (28055970) | Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM. | Full reference... |