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Molecular Profile | ATM I1453fs |
Therapy | Radiotherapy |
Indication/Tumor Type | tongue squamous cell carcinoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
ATM I1453fs | tongue squamous cell carcinoma | predicted - sensitive | Radiotherapy | Case Reports/Case Series | Actionable | In a retrospective analysis, radiotherapy treatment resulted in a complete metabolic response lasting at least 34 months in a patient with squamous cell carcinoma of the tongue, and the patient was found to harbor ATM I1453fs (PMID: 28055970). | 28055970 |
PubMed Id | Reference Title | Details |
---|---|---|
(28055970) | Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM. | Full reference... |