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| Molecular Profile | NRAS Q61K |
| Therapy | IHMT-RAF-128 |
| Indication/Tumor Type | thyroid cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| NRAS Q61K | thyroid cancer | sensitive | IHMT-RAF-128 | Preclinical - Cell culture | Actionable | In a preclinical study, IHMT-RAF-128 inhibited proliferation in a thyroid cancer cell line harboring NRAS Q61K in culture (PMID: 37164118). | 37164118 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (37164118) | Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment. | Full reference... |