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| Molecular Profile | RET V804M |
| Therapy | FHND5071 |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| RET V804M | Advanced Solid Tumor | predicted - sensitive | FHND5071 | Preclinical - Cell culture | Actionable | In a preclinical study, FHND5071 inhibited Ret phosphorylation and proliferation in cells expressing RET V804M in culture (Cancer Res (2023) 83 (8_Supplement): LB330). | detail... |
| PubMed Id | Reference Title | Details |
|---|---|---|
| Abstract LB330: FHND5071: a selective RET inhibitor with unique pharmacokinetic profile | Full reference... |