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Molecular Profile | FLT3 I836T |
Therapy | KW-2449 |
Indication/Tumor Type | hematologic cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FLT3 I836T | hematologic cancer | sensitive | KW-2449 | Preclinical - Cell culture | Actionable | In a preclinical study, KW-2449 inhibited viability in transformed cells expressing FLT3 I836T in culture (PMID: 28077790). | 28077790 |
PubMed Id | Reference Title | Details |
---|---|---|
(28077790) | FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors. | Full reference... |