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| Molecular Profile | CTNNB1 amp |
| Therapy | CWP232291 |
| Indication/Tumor Type | acute myeloid leukemia |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| CTNNB1 amp | acute myeloid leukemia | predicted - sensitive | CWP232291 | Phase I | Actionable | In a Phase I trial, CWP232291 reduced beta-catenin expression and demonstrated safety and preliminary efficacy in acute myeloid leukemia (J Clin Oncol (Meeting Abstracts) 2015 33: 7044)). | detail... |
| PubMed Id | Reference Title | Details |
|---|---|---|
| Phase 1 study of CWP232291 in relapsed/refractory acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). | Full reference... |