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Molecular Profile | APC Q1338* |
Therapy | JW67 |
Indication/Tumor Type | colorectal cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
APC Q1338* | colorectal cancer | sensitive | JW67 | Preclinical | Actionable | In a preclinical study, JW67 inhibited Wnt signaling and decreased proliferation of colorectal cancer cells harboring APC Q1338* in culture (PMID: 21199802). | 21199802 |
PubMed Id | Reference Title | Details |
---|---|---|
(21199802) | Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth. | Full reference... |