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| Molecular Profile | APC Q1338* |
| Therapy | JW67 |
| Indication/Tumor Type | colorectal cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| APC Q1338* | colorectal cancer | sensitive | JW67 | Preclinical | Actionable | In a preclinical study, JW67 inhibited Wnt signaling and decreased proliferation of colorectal cancer cells harboring APC Q1338* in culture (PMID: 21199802). | 21199802 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (21199802) | Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth. | Full reference... |