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| Molecular Profile | FLT3 G846D |
| Therapy | Midostaurin |
| Indication/Tumor Type | hematologic cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FLT3 G846D | hematologic cancer | sensitive | Midostaurin | Preclinical - Cell culture | Actionable | In a preclinical study, Rydapt (midostaurin) inhibited growth of cells expressing FLT3 G846D in culture (PMID: 38049555). | 38049555 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (38049555) | Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia. | Full reference... |