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Molecular Profile | FLT3 G846D |
Therapy | Sorafenib |
Indication/Tumor Type | hematologic cancer |
Response Type | resistant |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FLT3 G846D | hematologic cancer | resistant | Sorafenib | Preclinical - Cell culture | Actionable | In a preclinical study, a cell line expressing FLT3 G846D was resistant to Nexavar (sorafenib) in culture (PMID: 38049555). | 38049555 |
PubMed Id | Reference Title | Details |
---|---|---|
(38049555) | Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia. | Full reference... |