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Molecular Profile | BRAF V600X |
Therapy | Vemurafenib |
Indication/Tumor Type | thyroid cancer |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600X | thyroid cancer | predicted - sensitive | Vemurafenib | Case Reports/Case Series | Actionable | In a Phase II trial, treatment with Zelboraf (vemurafenib) resulted in an overall response rate of 29% (2/7), with 1 complete response and 1 partial response, in patients with anaplastic thyroid cancer patients with BRAF V600 mutations (PMID: 26287849; NCT01524978). | 26287849 |
PubMed Id | Reference Title | Details |
---|---|---|
(26287849) | Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations. | Full reference... |