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Molecular Profile BRAF V600X
Therapy Vemurafenib
Indication/Tumor Type cholangiocarcinoma
Response Type predicted - sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF V600X cholangiocarcinoma predicted - sensitive Vemurafenib Case Reports/Case Series Actionable In a Phase II trial, treatment with Zelboraf (vemurafenib) resulted in partial response in 12% (1/8) and stable disease in 50% (4/8) of cholangiocarcinoma patients with BRAF V600 mutations (PMID: 26287849; NCT01524978). 26287849
PubMed Id Reference Title Details
(26287849) Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations. Full reference...