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Molecular Profile | NRAS Q61R |
Therapy | GDC-0623 |
Indication/Tumor Type | ameloblastoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
NRAS Q61R | ameloblastoma | sensitive | GDC-0623 | Preclinical - Cell culture | Actionable | In a preclinical study, GDC-0623 inhibited Erk phosphorylation and viability of an ameloblastoma cell line harboring NRAS Q61R in culture (PMID: 35689405). | 35689405 |
PubMed Id | Reference Title | Details |
---|---|---|
(35689405) | New Ameloblastoma Cell Lines Enable Preclinical Study of Targeted Therapies. | Full reference... |