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Molecular Profile | BRAF V600E |
Therapy | Tovorafenib |
Indication/Tumor Type | melanoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E | melanoma | sensitive | Tovorafenib | Preclinical - Cell culture | Actionable | In a preclinical study, Ojemda (tovorafenib) treatment inhibited viability of a melanoma cell line harboring BRAF V600E in culture (PMID: 31618628). | 31618628 |
PubMed Id | Reference Title | Details |
---|---|---|
(31618628) | Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses. | Full reference... |