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| Molecular Profile | MDM2 amp |
| Therapy | N/A |
| Indication/Tumor Type | dedifferentiated liposarcoma |
| Response Type | not applicable |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| MDM2 amp | dedifferentiated liposarcoma | not applicable | N/A | Clinical Study | Diagnostic | MDM2 amplification aids in the diagnosis of dedifferentiated liposarcoma (PMID: 36674856, PMID: 35074968, PMID: 18500263, PMID: 33799733). | 33799733 36674856 35074968 18500263 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (33799733) | MDM2 Amplified Sarcomas: A Literature Review. | Full reference... |
| (35074968) | Detection of MDM2 gene amplification on tissue microarray-based Fluorescence In-Situ Hybridization (FISH) in well-differentiated and dedifferentiated liposarcomas, displaying a wide morphological spectrum: A validation study at a tertiary cancer referral centre. | Full reference... |
| (36674856) | FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations. | Full reference... |
| (18500263) | Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms. | Full reference... |