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| Molecular Profile | ERBB4 over exp |
| Therapy | Duvelisib |
| Indication/Tumor Type | marginal zone lymphoma |
| Response Type | resistant |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| ERBB4 over exp | marginal zone lymphoma | resistant | Duvelisib | Preclinical - Cell culture | Actionable | In a preclinical study, a marginal zone lymphoma cell line with ERBB4 overexpression demonstrated resistance to Copiktra (duvelisib) in culture (PMID: 38052765). | 38052765 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (38052765) | ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms. | Full reference... |