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Molecular Profile | HRAS Q61H |
Therapy | BTX-7312 |
Indication/Tumor Type | uterine cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
HRAS Q61H | uterine cancer | sensitive | BTX-7312 | Preclinical - Cell culture | Actionable | In a preclinical study, BTX-7312 inhibited proliferation of a uterine cancer cell line harboring HRAS Q61H in 3D culture (PMID: 38224565). | 38224565 |
PubMed Id | Reference Title | Details |
---|---|---|
(38224565) | Cereblon-based Bifunctional Degrader of SOS1, BTX-6654, Targets Multiple KRAS Mutations and Inhibits Tumor Growth. | Full reference... |