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Molecular Profile | DNMT3A mutant |
Therapy | N/A |
Indication/Tumor Type | acute myeloid leukemia |
Response Type | not applicable |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
DNMT3A mutant | acute myeloid leukemia | not applicable | N/A | Clinical Study | Prognostic | In clinical analyses, mutations in DNMT3A were associated with poor prognosis and shorter overall survival in patients with acute myeloid leukemia (PMID: 22490330, PMID: 21881046, PMID: 21670448). | 22490330 21881046 21670448 |
PubMed Id | Reference Title | Details |
---|---|---|
(22490330) | Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia. | Full reference... |
(21881046) | Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia. | Full reference... |
(21670448) | Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia. | Full reference... |