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Molecular Profile | BRAF V600E |
Therapy | Cetuximab + Encorafenib |
Indication/Tumor Type | colon neuroendocrine neoplasm |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E | colon neuroendocrine neoplasm | predicted - sensitive | Cetuximab + Encorafenib | Case Reports/Case Series | Actionable | In a clinical case study, treatment with the combination of Erbitux (cetuximab) and Braftovi (encorafenib) resulted in reduced liver metastasis and a progression-free survival of 14 months in a patient with colorectal neuroendocrine carcinoma harboring BRAF V600E (PMID: 37981300). | 37981300 |
PubMed Id | Reference Title | Details |
---|---|---|
(37981300) | BRAF V600E-mutated Colorectal Neuroendocrine Carcinoma Effectively Treated with a Chemotherapy Protocol for BRAF-mutated Metastatic Colorectal Cancer: A Case Report. | Full reference... |