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Molecular Profile | BRAF V600E |
Therapy | Vemurafenib |
Indication/Tumor Type | childhood pilocytic astrocytoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E | childhood pilocytic astrocytoma | predicted - sensitive | Vemurafenib | Case Reports/Case Series | Actionable | In a clinical case study, Zelboraf (vemurafenib) treatment resulted in a partial response in a pediatric patient with pilocytic astrocytoma harboring BRAF V600E (PMID: 38976815). | 38976815 |
PubMed Id | Reference Title | Details |
---|---|---|
(38976815) | Midline Low-Grade Gliomas of Early Childhood: Focus on Targeted Therapies. | Full reference... |