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Molecular Profile BRAF V600E
Therapy RGT-018
Indication/Tumor Type melanoma
Response Type no benefit

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF V600E melanoma no benefit RGT-018 Preclinical - Cell culture Actionable In a preclinical study, RGT-018 did not inhibit proliferation of melanoma cells harboring BRAF V600E in 3D culture (PMID: 39087485). 39087485
PubMed Id Reference Title Details
(39087485) Discovery of RGT-018: a Potent, Selective and Orally Bioavailable SOS1 Inhibitor for KRAS-driven Cancers. Full reference...