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| Molecular Profile | FGFR2 N550H |
| Therapy | KIN-3248 |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 N550H | Advanced Solid Tumor | predicted - sensitive | KIN-3248 | Preclinical - Biochemical | Actionable | In a preclinical study, KIN-3248 inhibited kinase activity of FGFR2 N550H in an in vitro assay (PMID: 38437671). | 38437671 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (38437671) | The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations. | Full reference... |