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| Molecular Profile | PTEN del |
| Therapy | GSK2636771 |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | no benefit |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| PTEN del | Advanced Solid Tumor | no benefit | GSK2636771 | Case Reports/Case Series | Actionable | In a Phase I trial, patients with advanced solid tumors deficient in PTEN lacked benefit from GSK2636771 (PMID: 26117819). | 26117819 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (26117819) | Drugging PI3K in cancer: refining targets and therapeutic strategies. | Full reference... |