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Molecular Profile BRAF V600E
Therapy Cetuximab + Encorafenib
Indication/Tumor Type pseudomyxoma peritonei
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF V600E pseudomyxoma peritonei sensitive Cetuximab + Encorafenib Preclinical - Pdx & cell culture Actionable In a preclinical study, treatment with the combination of Braftovi (encorafenib) and Erbitux (cetuximab) inhibited viability and induced apoptosis in a patient-derived pseudomyxoma peritonei cell line harboring BRAF V600E in culture and inhibited tumor growth and improved survival of a patient-derived xenograft (PDX) model (PMID: 39018564). 39018564
PubMed Id Reference Title Details
(39018564) Precision Oncology and Systemic Targeted Therapy in Pseudomyxoma Peritonei. Full reference...