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Molecular Profile | BRAF D594N |
Therapy | Erlotinib |
Indication/Tumor Type | lung adenocarcinoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF D594N | lung adenocarcinoma | predicted - sensitive | Erlotinib | Case Reports/Case Series | Actionable | In a clinical case study, Tarceva (erlotinib) treatment resulted in a persistent complete response that was ongoing after 12 years in a patient with lung adenocarcinoma harboring BRAF D594N with brain and lymph node metastases (PMID: 39637338). | 39637338 |
PubMed Id | Reference Title | Details |
---|---|---|
(39637338) | Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations. | Full reference... |