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Molecular Profile | FGFR3 wild-type |
Therapy | SSR128129E |
Indication/Tumor Type | myeloid neoplasm |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR3 wild-type | myeloid neoplasm | sensitive | SSR128129E | Preclinical | Actionable | In a preclinical study, SSR128129E inhibited proliferation of myeloma cells expressing wild-type FGFR3 in culture (PMID: 23597562). | 23597562 |
PubMed Id | Reference Title | Details |
---|---|---|
(23597562) | Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. | Full reference... |