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| Molecular Profile | FGFR3 K650E |
| Therapy | SSR128129E |
| Indication/Tumor Type | myeloid neoplasm |
| Response Type | no benefit |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR3 K650E | myeloid neoplasm | no benefit | SSR128129E | Preclinical | Actionable | In a preclinical study, SSR128129E did not inhibit proliferation of myeloma cells expressing FGFR3 K650E in culture (PMID: 23597562). | 23597562 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23597562) | Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. | Full reference... |