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Molecular Profile | FGFR3 over exp |
Therapy | SU5402 |
Indication/Tumor Type | urinary bladder cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR3 over exp | urinary bladder cancer | sensitive | SU5402 | Preclinical | Actionable | In a preclinical study, SU5402 inhibited growth of bladder cancer cells over expressing wild-type FGFR3 in culture (PMID: 21119661). | 21119661 |
PubMed Id | Reference Title | Details |
---|---|---|
(21119661) | Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo. | Full reference... |