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| Molecular Profile | FGFR2 wild-type |
| Therapy | FIIN-1 |
| Indication/Tumor Type | endometrial carcinoma |
| Response Type | resistant |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 wild-type | endometrial carcinoma | resistant | FIIN-1 | Preclinical | Actionable | In a preclinical study, an endometrial carcinoma cell line harboring wild-type FGFR2 was resistant to FIIN-1-induced growth inhibition in culture (PMID: 20338520). | 20338520 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (20338520) | A structure-guided approach to creating covalent FGFR inhibitors. | Full reference... |