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| Molecular Profile | BRIP1 H396D |
| Therapy | Cisplatin |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| BRIP1 H396D | Advanced Solid Tumor | sensitive | Cisplatin | Preclinical - Cell culture | Actionable | In a preclinical study, Platinol (cisplatin) treatment inhibited viability of a cell line expressing BRIP1 H396D in culture (PMID: 33619228). | 33619228 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (33619228) | Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1. | Full reference... |