Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Molecular Profile | BARD1 T719R |
| Therapy | Cisplatin |
| Indication/Tumor Type | ovarian cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| BARD1 T719R | ovarian cancer | sensitive | Cisplatin | Preclinical - Cell culture | Actionable | In a preclinical study, an ovarian cancer cell line expressing BARD1 T719R was sensitive to Platinol (cisplatin) in culture, demonstrating decreased colony formation (PMID: 39387837). | 39387837 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (39387837) | Functional Analysis of BARD1 Missense Variants on Homology-Directed Repair in Ovarian and Breast Cancers. | Full reference... |