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| Molecular Profile | KIT Q575_P577delinsH |
| Therapy | Lenvatinib |
| Indication/Tumor Type | thymus squamous cell carcinoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| KIT Q575_P577delinsH | thymus squamous cell carcinoma | predicted - sensitive | Lenvatinib | Case Reports/Case Series | Actionable | In a clinical case study, Lenvima (lenvatinib) treatment resulted in a partial response with treatment lasting 10 months in a patient with metastatic thymic squamous cell carcinoma harboring KIT Q575_P577delinsH (PMID: 38706977). | 38706977 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (38706977) | Rapid Response to Lenvatinib and Disease Flare After Discontinuation in a Patient With Thymic Carcinoma Harboring KIT Exon 11 Mutation: A Case Report. | Full reference... |