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| Molecular Profile | RAD51D S207L |
| Therapy | Cisplatin |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| RAD51D S207L | Advanced Solid Tumor | predicted - sensitive | Cisplatin | Preclinical - Cell culture | Actionable | In a preclinical study, cells expressing RAD51D S207L demonstrated decreased survival when treated with Platinol (cisplatin) in culture (PMID: 28646019). | 28646019 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (28646019) | Functionally Null RAD51D Missense Mutation Associates Strongly with Ovarian Carcinoma. | Full reference... |