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| Molecular Profile | PALB2 L1070P |
| Therapy | Cisplatin |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| PALB2 L1070P | Advanced Solid Tumor | sensitive | Cisplatin | Preclinical - Cell culture | Actionable | In a preclinical study, Platinol (cisplatin) decreased survival of cells expressing PALB2 L1070P in culture (PMID: 31636395). | 31636395 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (31636395) | Functional characterization of 84 PALB2 variants of uncertain significance. | Full reference... |