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Molecular Profile | KIT V560del |
Therapy | Imatinib |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
KIT V560del | Advanced Solid Tumor | sensitive | Imatinib | Preclinical | Actionable | In a preclinical study, Gleevec (imatinib) inhibited growth of transformed cell lines over expressing KIT V560del in culture (PMID: 19861435). | 19861435 |
PubMed Id | Reference Title | Details |
---|---|---|
(19861435) | Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas. | Full reference... |