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| Molecular Profile | PTEN wild-type |
| Therapy | GSK2256098 |
| Indication/Tumor Type | uterine cancer |
| Response Type | decreased response |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| PTEN wild-type | uterine cancer | decreased response | GSK2256098 | Preclinical | Actionable | In a preclinical study, GSK2256098 treatment resulted in a decreased response in uterine cancer cells with PTEN wild-type versus uterine cancer cells harboring a PTEN mutation (PMID: 25833835). | 25833835 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (25833835) | PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer. | Full reference... |