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| Molecular Profile | PTEN loss |
| Therapy | GSK2636771 |
| Indication/Tumor Type | prostate cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| PTEN loss | prostate cancer | sensitive | GSK2636771 | Preclinical | Actionable | In a preclinical study, GSK2636771 inhibited viability of prostate cancer cell lines harboring PTEN deficiency in culture (PMID: 23674493). | 23674493 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23674493) | PI3K pathway dependencies in endometrioid endometrial cancer cell lines. | Full reference... |