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| Molecular Profile | AXL positive |
| Therapy | Bemcentinib |
| Indication/Tumor Type | head and neck squamous cell carcinoma |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| AXL positive | head and neck squamous cell carcinoma | sensitive | Bemcentinib | Preclinical | Actionable | In a preclinical study, Bemcentinib (BGB-324) inhibited proliferation and invasion of head and neck squamous cell carcinoma cell lines positive for Axl expression in culture (PMID: 25767293). | 25767293 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (25767293) | AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma. | Full reference... |