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Molecular Profile TP53 wild-type
Therapy CTX-1
Indication/Tumor Type acute myeloid leukemia
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
TP53 wild-type acute myeloid leukemia sensitive CTX-1 Preclinical Actionable In a preclinical study, CTX-1 improved survival time in mouse models of acute myeloid leukemia using TP53 wild-type primary human acute myeloid leukemia cells (PMID: 26883273). 26883273
PubMed Id Reference Title Details
(26883273) Identification of a Small Molecule That Overcomes HdmX-Mediated Suppression of p53. Full reference...