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Molecular Profile | PIK3CA H1047R |
Therapy | A66 |
Indication/Tumor Type | ovarian cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
PIK3CA H1047R | ovarian cancer | sensitive | A66 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, A66 delayed tumor growth in an ovarian cancer cell line xenograft model harboring PIK3CA H1047R (PMID: 21668414). | 21668414 |
PubMed Id | Reference Title | Details |
---|---|---|
(21668414) | A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types. | Full reference... |