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Molecular Profile | FGFR1 positive |
Therapy | Fexagratinib |
Indication/Tumor Type | synovial sarcoma |
Response Type | decreased response |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR1 positive | synovial sarcoma | decreased response | Fexagratinib | Preclinical - Cell culture | Actionable | In a preclinical study, synovial sarcoma cells with moderate Fgfr1 expression level demonstrated decreased response to AZD4547 in culture (PMID: 27535980). | 27535980 |
PubMed Id | Reference Title | Details |
---|---|---|
(27535980) | Targeting Fibroblast Growth Factor Receptor 1 for Treatment of Soft-Tissue Sarcoma. | Full reference... |