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Molecular Profile | FGFR2 amp |
Therapy | RO4987655 |
Indication/Tumor Type | colorectal adenocarcinoma |
Response Type | decreased response |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR2 amp | colorectal adenocarcinoma | decreased response | RO4987655 | Preclinical - Cell culture | Actionable | In a preclinical study, FGFR2 amplified colorectal adenocarcinoma cells demonstrated decreased response to RO4987655 in culture (PMID: 26438159). | 26438159 |
PubMed Id | Reference Title | Details |
---|---|---|
(26438159) | ERK Signal Suppression and Sensitivity to CH5183284/Debio 1347, a Selective FGFR Inhibitor. | Full reference... |