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| Molecular Profile | FGFR2 amp |
| Therapy | RO4987655 |
| Indication/Tumor Type | colorectal adenocarcinoma |
| Response Type | decreased response |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 amp | colorectal adenocarcinoma | decreased response | RO4987655 | Preclinical - Cell culture | Actionable | In a preclinical study, FGFR2 amplified colorectal adenocarcinoma cells demonstrated decreased response to RO4987655 in culture (PMID: 26438159). | 26438159 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (26438159) | ERK Signal Suppression and Sensitivity to CH5183284/Debio 1347, a Selective FGFR Inhibitor. | Full reference... |