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Molecular Profile KIT L576P
Therapy Imatinib
Indication/Tumor Type melanoma
Response Type unknown

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
KIT L576P melanoma unknown Imatinib Case Reports/Case Series Actionable In a clinical case study, Gleevec (imatinib) treatment resulted in initial tumor reduction, but was followed by disease progression at all tumor sites in a patient with metastasized labial melanoma harboring KIT L576P (PMID: 20372153). 20372153
PubMed Id Reference Title Details
(20372153) Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT. Full reference...